The Adrenal Gland

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Enlightening the adrenal gland.

The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study Ishida et al., 2005 [this issue of Cell Metabolism) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway.

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The role of inflammation has been shown in the pathogenesis of epilepsy, while glucocorticoids and adrenaline have anti-inflammatory effects. The aim of the present study was to investigate the effects of adrenaline, prednisolone, and indomethacin on caffeine-induced epilepsy (epileptiform activity) in rats and to examine the mechanism of the pro-epileptic effect of indomethacin. The adrenalect...

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[Cysts of the adrenal gland].

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ژورنال

عنوان ژورنال: Nature

سال: 1957

ISSN: 0028-0836,1476-4687

DOI: 10.1038/1791209b0